Skip to main content
. Author manuscript; available in PMC: 2014 Nov 14.
Published in final edited form as: EcoSal Plus. 2009 Aug;3(2):10.1128/ecosalplus.4.4.2. doi: 10.1128/ecosalplus.4.4.2

Fig. 8. Models of the release of the lagging strand polymerase.

Fig. 8

Lagging strand polymerase must be able to dissociate from an Okazaki fragment in order to be recycled to new RNA primers during synthesis of numerous Okazaki fragments. In premature release (left), the polymerase dissociates before finishing the Okazaki fragment, leaving behind a single strand DNA gap. In collision release (right) the lagging strand polymerase completes the Okazaki fragment to a nick and Pol III then disengages from the β clamp. See text for details.