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In human duodenal and colonic tissues, CXCR1 is expressed on the apical surface of villus enterocytes and is absent in the crypts. Duodenum and colon biopsies stained with anti-occludin (red), DRAQ5 (blue) and anti-CXCR1 (green). In villus enterocytes, CXCR1 is located on the apical membrane (sections of duodenum (a) and colon (c)), and surrounding the nuclei of cells in the lamina propria (a, arrow). CXCR1 is absent in the enterocytes lining the crypts of duodenum (b) and colon (d).
