Table 1.

CR Genes Identified in Holocentric and Nonholocentric Insecta

Class	Order	Species	Protein Identifier^a	Protein Sequence Identity^b (%)	Protein Length	Conserved Protein Domains
Class	Order	Species	Protein Identifier^a	Protein Sequence Identity^b (%)	Protein Length	HTH_CENP-B_N	HTH_Tnp_Tc5
Insecta	Diptera	Drosophila melanogaster	CAG (CG12346)	100	225	X	X
		D. simulans	GD15259	97.22	111	X	—
		D. sechelia	GM20484	94.67	225	X	X
		D. yakuba	GE13064	92.44	225	X	X
		D. erecta	GG22708	93.24	207	X	X
		D. ananassae	GF13390	59.11	222	X	X
		D. pseudoobscura	GA11571	57.46	228	X	X
		D. persimilis	GL17090	58.77	228	X	X
		D. willistoni	GK19073	40.29	222	X	X
		D. virilis	GJ16124	39.81	227	X	X
Insecta	Lepidoptera	Bombyx mori	BGIBMGA013031	32.09	278	X	X
			BGIBMGA008012	26.35	501	X	X
			BGIBMGA007903	25	468	X	X
			BGIBMGA013624	29.63	722	X	X
Insecta	Lepidoptera	Heliconius melpomene	HMEL009793	35.38	255	X	X
			HMEL010729	33.8	295	X	X
			HMEL014790	31.55	533	X	X
			HMEL007960	50	533	X	X
			HMEL011593	35.38	192	X	X
Insecta	Lepidoptera	Helicoverpa armigera	94B11_25*	22.22^#	488	X	X
Insecta	Lepidoptera	Spodoptera frugiperda	72F01*	23.61^#	488	X	X
Insecta	Coleoptera	Tribolium castaneum	TC003750	26.39	1175	X	X
			TC001653	30	486	X	—
			TC005011	51.49	212	—	X

^aAll sequences can be downloaded from Ensembl Metazoa except those with an “*” that can be downloaded from LepidoDB.

^bProtein sequence identity estimated using BLASTp except for those with an “^#” estimated using ClustalW (see Materials and Methods).