Table 3. Changes in systolic blood pressure (SBP) with liraglutide versus placebo at the end of 26 weeks by concomitant antihypertensive medication status.
Data are last observation carried forward for the intention-to-treat population.
| n | Least squares mean change (mmHg) | Standard error | P value | ||
|---|---|---|---|---|---|
| Patients receiving concomitant antihypertensive medications | |||||
| Treatment | Liraglutide 1.2 mg | 560 | −1.44 | 0.87 | 0.0989 |
| Liraglutide 1.8 mg | 884 | −2.02 | 0.78 | 0.0105 | |
| Placebo | 358 | +0.61 | 0.95 | 0.5187 | |
| Estimated treatment differences | Liraglutide 1.2 mg – Placebo | −2.05 | 0.86 | 0.0171 | |
| Liraglutide 1.8 mg – Placebo | −2.63 | 0.80 | 0.0010 | ||
| Patients not receiving concomitant antihypertensive medications | |||||
| Treatment | Liraglutide 1.2 mg | 320 | −4.42 | 0.97 | <0.0001 |
| Liraglutide 1.8 mg | 467 | −4.06 | 0.86 | <0.0001 | |
| Placebo | 162 | −2.21 | 1.18 | 0.0612 | |
| Estimated treatment differences | Liraglutide 1.2 mg – Placebo | −2.21 | 1.21 | 0.0680 | |
| Liraglutide 1.8 mg – Placebo | −1.85 | 1.15 | 0.1058 | ||