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Population Pharmacokinetic Analysis
| Variable | Population Estimate (±Standard Error) |
|---|---|
| Clearance (Cl/F) | 6.66 ± 1.10 L/h or 0.17 ± 0.03 L/h/kg |
| Volume of distribution of central compartment (Vc) | 26.9 ± 7.7 L |
| Volume of distribution of peripheral compartment (Vp) | 630 ± 171 L |
| Intercompartment clearance (Q) | 4.62 ± 2.00 L/h |
| Absorption rate constant (ka) | 0.0535 ± 0.0104 h-1 |
