(A) Frequency of gut Th17 cells, (B) Th22 cells, and (C) Th1 cells in HIV-uninfected, chronic ART-naïve, long-term ART treated and ART-naïve EC men at baseline. (D) Polyfunctional capacity of gut Th17 cells in ECs was similar to the HIV-uninfected controls and higher than chronically HIV-infected participants. (E) Each combination of IL-22, IFNγ and TNFα production by Th17 cells is shown; horizontal lines indicate the median and box plots depict the interquartile range. * indicates P<0.05