Table 1.
Baseline characteristics of patients with ST segment elevation myocardial infarction with preserved left ventricular systolic function according to treatment at discharge. Figures are numbers (percentage) of patients unless stated otherwise
| Variables | ARB (n=1185) | ACEI (n=4564) | No RAS (n=949) | P value | |
|---|---|---|---|---|---|
| ARB v ACEI | ARB v no RAS | ||||
| Mean (SD) age (years) | 63.0 (12.9) | 61.4 (12.7 | 62.8 (12.8) | <0.001 | 0.78 |
| Men | 867 (73.2) | 3491 (76.5) | 699 (73.7) | 0.02 | 0.80 |
| Medical history: | |||||
| Diabetes mellitus | 279 (23.5) | 1038 (22.7) | 220 (23.2) | 0.56 | 0.84 |
| Hypertension | 620 (52.3) | 2001 (43.8) | 385 (40.6) | <0.001 | <0.001 |
| Dyslipidaemia | 104 (8.8) | 502 (11.0) | 98 (10.3) | 0.03 | 0.22 |
| Smoking | 508 (42.9) | 2288 (50.1) | 460 (48.5) | <0.001 | 0.01 |
| Chronic kidney disease | 9 (0.8) | 27 (0.6) | 7 (0.7) | 0.51 | 0.95 |
| Family history of CAD | 90 (7.6) | 385 (8.4) | 66 (7.0) | 0.35 | 0.57 |
| Previous history of MI | 67 (5.7) | 198 (4.3) | 50 (5.3) | 0.05 | 0.70 |
| Previous history of PCI | 66 (5.6) | 161 (3.5) | 43 (4.5) | 0.001 | 0.28 |
| Previous CABG | 3 (0.3) | 10 (0.2) | 6 (0.6) | 0.74 | 0.20 |
| Previous CVA | 61 (5.1) | 222 (4.9) | 37 (3.9) | 0.69 | 0.17 |
| Previous history of heart failure | 16 (1.4) | 17 (0.4) | 5 (0.5) | <0.001 | 0.06 |
| Killip class ≥III on admission | 110 (9.3) | 404 (8.9) | 124 (13.1) | 0.64 | 0.005 |
| Mean (SD) left ventricle ejection fraction | 53.8 (9.2) | 54.1 (8.8) | 53.5 (9.4) | 0.33 | 0.43 |
| Mean (SD) serum creatinine (µmol/L) | 97.24 (81.33) | 91.94 (64.53) | 97.24 (60.11) | 0.02 | 0.96 |
| Mean (SD) symptom to balloon time (min) | 369.8 (300.3) | 363.4 (290.4) | 383.6 (304.9) | 0.50 | 0.30 |
| Drugs at discharge: | |||||
| Aspirin | 1175 (99.2) | 4529 (99.2) | 920 (96.9) | 0.79 | <0.001 |
| Clopidogrel | 1174 (99.1) | 4474 (98.0) | 909 (95.8) | 0.02 | <0.001 |
| β blocker | 956 (80.7) | 3961 (86.8) | 570 (60.1) | <0.001 | <0.001 |
| Statins | 967 (81.6) | 3810 (83.5) | 755 (79.6) | 0.13 | 0.23 |
ARB=angiotensin receptor blocker; ACEI=angiotensin converting enzyme inhibitor; CABG=coronary artery bypass grafting; CAD=coronary artery disease; CVA=cerebrovascular event; MI=myocardial infarction; PCI=percutaneous coronary intervention; RAS=renin angiotension system.