Figure 1.
Potential sources of variability to clinical response to cisplatin treatment. Abbreviations: DNA, deoxyribonucleic acid; GSTs, glutathione S-Transferases; NER, nucleotide excision repair; LPR2, Low Phosphate Root2; SLC31A1 (CTR1), solute carrier family 31 (copper transporter), member 1; SLC22A2, solute carrier family 22 (organic cation transporter), member 2; ERCCs, Excision Repair Cross Complementing group of proteins; XPC, Xeroderma Pigmentosum Group C Protein.