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Treatment Groups
| Ut | Untreated group |
| Top | Topical delivery group |
| Sc-high | High-dose subconjunctival group |
| Sc-low | Low-dose subconjunctival group |
| Mn-1 bolus | 1-microneedle bolus delivery group |
| Mn-4 bolus | 4-microneedle bolus delivery group |
| Mn-1 ×3 | 1-microneedle, 3 doses, delivery group |
| Mn-placebo | 1-microneedle placebo group |
| Mn-hollow | Hollow microneedle bolus delivery group |
