TABLE 1.
Characteristics of CHARGE participating cohorts1
| Discovery cohorts |
|||
| Participant characteristics | FOS (n = 1607) | Health ABC (n = 531) | Second-stage cohort: MESA (n = 265) |
| Age, y | 56.7 ± 10.92 | 74.8 ± 2.9 | 61.9 ± 9.9 |
| Sex, M/F, n | 760/847 | 242/289 | 120/145 |
| BMI, kg/m2 | 28.2 ± 5.3 | 26.8 ± 4.2 | 27.7 ± 4.9 |
| Waist circumference, cm | 99.4 ± 5.5 | 99.8 ± 12.13 | 97.7 ± 14.9 |
| Circulating phylloquinone, nmol/L | 0.9 ± 2.5 | 1.1 ± 1.5 | 1.3 ± 1.4 |
| Circulating triglycerides, mg/dL | 134.7 ± 89.3 | 158.9 ± 96.5 | 132.6 ± 80.8 |
| Total cholesterol, mg/dL | 200.1 ± 35.8 | 208.7 ± 38.3 | 196.3 ± 35.2 |
| HDL cholesterol, mg/dL | 53.5 ± 16.6 | 52.6 ± 16.5 | 53.6 ± 15.9 |
| Fasting glucose, mg/dL | 102.8 ± 24.7 | 98.7 ± 23.6 | 90.2 ± 18.6 |
| Dietary intake | |||
| Total energy, kcal/d | 1824 ± 607 | 1796 ± 660 | 1482 ± 661 |
| Total proteins, g/d | 78.3 ± 26.8 | 64.6 ± 25.7 | 57.8 ± 28.2 |
| Total carbohydrates, g/d | 228.5 ± 84.4 | 237.6 ± 86.9 | 183.5 ± 82.3 |
| Total fats, g/d | 62.5 ± 27.5 | 67.5 ± 33.5 | 53.66 ± 28.7 |
| Vegetables,4 1/2 cup, servings/d | 1.9 ± 1.1 | 3.1 ± 1.7 | 2.3 ± 1.2 |
| Vitamin K, μg/d | 156 ± 108 | NA | 137 ± 130 |
1
CHARGE, Cohorts for Heart and Aging Research in Genomic Epidemiology; FOS, Framingham Offspring Study; Health ABC, Health, Aging, and Body Composition; MESA, Multi-Ethnic Study of Atherosclerosis; NA, not available.
2
Mean; 95% CI in parentheses (all such values).
3
Abdominal obesity.
4
Vegetable intake included red, orange, and yellow vegetables and green leafy vegetables, excluding legumes and potatoes.