TABLE 2.
Rate of common infectious morbidity and selected clinical SIEs during the first 6 mo of life in African HIV-exposed, uninfected infants in the Kesho Bora RCT by infant feeding mode1
| Recalled infectious morbidity |
Clinical SIEs |
|||||
| Age interval and modality | Exposure, infant-months | Events | Rate/1000 infant-months | Exposure, infant-months | Events (deaths) | Rate/1000 infant-months |
| 0–2.9 mo | 2107 | 378 | 179 | 2206 | 27 (9) | 12.2 |
| Breastfeeding | ||||||
| Yes | 717 | 143 | 199 | 779 | 21 (7) | 27.0 |
| No | 1390 | 235 | 169 | 1427 | 6 (2) | 4.2 |
| Mode | ||||||
| Never breastfeeding | 469 | 87 | 186 | 488 | 15 (5) | 30.7 |
| Weaned | 247 | 56 | 227 | 291 | 6 (2) | 20.6 |
| Partially breastfeeding | 185 | 46 | 249 | 151 | 1 (0) | 6.6 |
| Predominantly breastfeeding | 363 | 63 | 174 | 387 | 2 (0) | 5.2 |
| EBF | 843 | 131 | 15.5 | 889 | 3 (2) | 3.4 |
| 3.0–6.0 mo | 1972 | 476 | 241 | 2098 | 25 (9) | 11.9 |
| Breastfeeding | ||||||
| Yes | 1207 | 327 | 271 | 1304 | 22 (8) | 16.9 |
| No | 765 | 149 | 195 | 794 | 3 (1) | 3.8 |
| Mode | ||||||
| Never breastfeeding | 432 | 109 | 252 | 467 | 4 (1) | 8.6 |
| Weaned | 775 | 218 | 281 | 837 | 18 (7) | 21.5 |
| Predominant breastfeeding | 319 | 61 | 191 | 211 | 1 (1) | 4.7 |
| Partial breastfeeding | 170 | 31 | 182 | 230 | 0 | 0 |
| EBF | 276 | 57 | 207 | 353 | 2 (0) | 5.7 |
1
Infectious morbidity comprised all episodes of diarrhea, fever, and vomiting. SIEs comprised all diarrheal and lower respiratory disease episodes; early neonatal events (from 0 to 7 d of age) were not included. EBF, exclusive breastfeeding; RCT, randomized controlled trial; SIE, serious infectious event.