Table 2.
Peri-procedural stroke or death, nonprocedural ipsilateral stroke, and restenosis ≥50%, stratified by degree of stenosis, length of stenosis, and plaque surface
| Peri-procedural stroke or death* | Nonprocedural ipsilateral stroke† | Ipsilateral residual or recurrent stenosis ≥50%† | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Degree of stenosis | OR (95% CI) | Degree of stenosis | HR (95% CI) | Degree of stenosis | HR (95% CI) | ||||
| n (%) | n [5-year risk % (SE)] | n [5-year risk % (SE)] | |||||||
| <Median | >Median | <Median | >Median | <Median | >Median | ||||
| EVT | 10 (10.0) | 13 (11.5) | 1.17 (0.50–2.74) | 7 [8.4 (3.3)] | 7 [5.7 (2.5)] | 0.92 (0.32–2.64) | 46 [55.5 (5.8)] | 53 [63.7 (6.1)] | 1.12 (0.75–1.67) |
| CEA | 11 (9.7) | 13 (13.3) | 1.42 (0.62–3.27) | 8 [7.6 (2.8)] | 5 [6.0 (2.6)] | 0.78 (0.25–2.40) | 23 [26.8 (5.1)] | 26 [27.0 (6.3)] | 1.41 (0.80–2.48) |
| Length of stenosis | Length of stenosis | Length of stenosis | |||||||
| <Threshold | >Threshold | <Threshold | >Threshold | <Threshold | >Threshold | ||||
| EVT | 9 (6.9) | 14 (17.1) | 2.79 (1.17–6.65)‡ 3.10 (1.19–8.13)†§ | 10 [7.0 (2.6)] | 4 [6.6 (3.2)] | 0.78 (0.25–2.49) | 55 [53.8 (5.8)] | 44 [70.1 (6.1)] | 1.68 (1.12–2.53)‡ 1.65 (1.08–2.51)‡§ |
| CEA | 9 (7.5) | 15 (16.5) | 2.43 (1.03–5.73)‡ 2.67 (1.07–6.68)‡§ | 8 [7.2 (2.7)] | 5 [6.6 (2.9)] | 0.84 (0.27–2.57) | 32 [35.6 (5.5]) | 17 [23.4 (5.2)] | 0.57 (0.32–1.04) |
| Plaque surface | Plaque surface | Plaque surface | |||||||
| Smooth | Irregular | Smooth | Irregular | Smooth | Irregular | ||||
| EVT | 8 (8.0) | 15 (13.3) | 1.76 (0.73–4.25) | 9 [9.1 (3.4)] | 5 [4.7 (2.3)] | 0.77 (0.44–1.34) | 51 [61.3 (6.1)] | 48 [39.3 (6.0)] | 0.85 (0.57–1.27) |
| CEA | 13 (12.5) | 11 (10.3) | 0.80 (0.35–1.85) | 7 [8.1 (3.0)] | 6 [5.8 (2.6)] | 0.93 (0.54–1.60) | 25 [29.7 (5.1)] | 24 (35.1 (6.2)] | 1.26 (0.72–2.22) |
Numbers in cells represent numbers of patients with end-point (percentage), and odds ratios (OR) with 95% confidence intervals (CI).
Numbers in cells represent numbers of patients with end-point [cumulative percentage incidence five-years after treatment (standard error)], and hazard ratios (HR) with 95% CI. Median degree of stenosis was 81% according to the method used in the NASCET trial. Threshold length of stenosis was 0.65 times the diameter of the distal common carotid artery, using the definition of length 2 (see text for details).
P < 0.05.
Adjusted for all anatomical parameters, age, gender, and vascular risk factors. Other OR and HR are unadjusted. EVT, endovascular treatment; CEA, carotid endarterectomy.