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. 2014 Mar 14;3(3):e13. doi: 10.1038/cti.2014.4

Table 1. Leishmania vaccine antigens being tested as candidate DNA vaccines.

Candidate antigen Models Disease Species Reference
LACK Dog, mice VL, CL L. donovani, L. chagasi, L. major, L. infantum 86, 87, 88, 89, 90
gp63 Mice, dogs CL, VL L. major, L. infantum 88, 90
KMP11 Mice CL, VL L. major L. donovani 91, 92, 93
CPB Dogs, mice VL, CL L. infantum, L. major 94, 95
ORFF Mice VL L. donovani 96
NH 36 Mice VL, CL L. chagasi, L. maxicana 97, 98
TRYP Dogs VL L. infantum 90
PSA-2 Mice CL L. major 88

Abbreviations: CPB, cysteine proteinase B; CL, cutaneous leishmaniasis; gp63, glycoprotein 63; KMP11, kinetoplastid membrane protein-11; LACK, Leishmania-activated C kinase; NH36, nucleoside hydrolase 36; ORFF, open reading frame F; PSA-2, promastigote surface antigen 2; TRYP, tryparedoxin peroxidase; VL, visceral leishmaniasis.