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. Author manuscript; available in PMC: 2014 Nov 14.
Published in final edited form as: Leuk Res. 2013 Jul 25;37(11):1440–1444. doi: 10.1016/j.leukres.2013.07.007

Table 1.

Criteria for assessment of response to therapy

International Working Group (IWG) consensus criteria for treatment response in myelofibrosis
Clinical Improvement (CI) in anemia

  1. A minimum 20 g/L increase in hemoglobin level or

  2. becoming transfusion independent for at least 8 week duration.*

    Transfusion dependency is defined by a history of at least 2 units of red blood cell transfusions in the last month.**

Delphi expert-consensus panel definitions of RBC-transfusion-dependence and – independence

  • becoming transfusion independent for at least 3 month duration.*

    Transfusion dependency is defined by a history of at least 2 units of red blood cell transfusions every month for last 3 months.**

*

applicable only for patients with baseline hemoglobin level of less than 100 g/L

**

for a hemoglobin level of less than 85 g/L that was not associated with clinically overt bleeding