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. 2014 Nov 14;464(Pt 2):231–239. doi: 10.1042/BJ20140606

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© 2014 This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (CC-BY)(http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.

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The rate of exchange of bound MANT-GDP for unlabelled GMP-PNP in the absence and presence of either the DH domain or the combined DH–PH domain of AKAP-Lbc. The decrease in fluorescence of MANT-GDP upon leaving RhoA was measured over time. The y-axis shows arbitrary fluorescence units. Measurements are plotted as the means±S.D. from three replicates.