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. 2014 Jan 23;53(8):2130–2133. doi: 10.1002/anie.201308636

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© 2014 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

This is an open access article under the terms of the Creative Commons Attribution Non-Commercial NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Scheme 1 — Hydrolysis of meropenem by the New Delhi Metallo-β-lactamase subclass 1 (NDM-1). The methyl groups of the substrate and product shown in green and red, respectively.