Table 2.
Summary of the laboratory findings for the PCR-positive patients in Study 1
| Characteristics | R11 | R12 | R39 |
|---|---|---|---|
| Sex, age in years | F, 25 | M, 51 | M, 12 |
| Previous diseases | None | None | None |
| Month | Oct | Feb | Aug |
| Duration of symptoms/days | 5 | 10 | 3 |
| Duration of facial palsy/days | 3 | 8 | NA |
| Duration of hearing loss/days | NA | NA | 5 |
| Fever (°C) | 37.4 | 35.5 | 36.8 |
| Headache | Yes | Yes | No |
| Dizziness | No | No | No |
| Stiff neck/neck pains | No/No | No/Yes | No |
| Photophobia | No | No | No |
| Body-aches, pains | No | Yes | No |
| Rash | No | No | No |
| Treatment (days) | |||
| AV | 10 | NA | NA |
| DC | NA | 10 (0.2 g/day) | 10 (0.2 g/day) |
| P | 7 | NA | 60 |
| C-reactive protein (mg/l) | <5 | <8 | 9 |
| WBC count (g/l) | 6.3 | 5.3 | 7.7 |
| CSF results | |||
| CSF cells total | <2 | 3 | 13 |
| Mono | 0 | 3 | 13 |
| Albumin (mg/l) | Normal | Normal | Normal |
| Blood glucose ratio | Normal | Normal | Normal |
| PCR results | |||
| Real-time PCR | |||
| gltA | pos | pos (2) | pos (2) |
| PCR+seq-id | |||
| ompB | neg | ND | ND |
| ompA | ND | ND | neg |
| 17 kDa | R.f | R.f (2) | R.f (2) |
| gltA | ND | neg | ND |
| Serology | |||
| Acute phase/s | |||
| Ric-MIF IgG | <64 | <64 | <64 |
| Ric-MIF IgM | 256 | 128 | 128 |
| Convalescent phase/s | |||
| Ric-MIF IgG | 128 | NA | NA |
| Ric-MIF IgM | 1024 | NA | NA |
| Borrelia (IU/ml) | |||
| Serum | neg | neg | neg |
| (Index) CSF | neg | neg | neg |
| TBE serology | ND | neg | ND |
| Herpes serology | neg | neg | neg |
| Serology enterovirus | neg | ND | ND |
| Brain CT | Normal | ND | Normal |
| Outcome | Restored | Restored | Restored |
AV, antiviral; DC, doxycycline; WBC, white blood cell; CSF, cerebrospinal fluid; P, penicillin; PCR, polymerase chain reaction; Ric, rickettsia; seq-id, sequence identity; TBE, tick borne encephalitis; R.f, R. felis; ND, not done; NA, not applicable; pos, positive; neg, negative; MIF, microimmunofluorescence.