. 2013 Aug 22;18(1):38–46. doi: 10.1111/hdi.12078

Table 1.

Polynomial regression models of Hb response

TSAT model	ΔHb(k + 1) = β₁ΔESA(k) + β₂ΔESA(k)TSAT(k) + β₃ΔESA(k)TSAT²(k) + β₄ΔESA(k)TSAT³(k) + β₅TSAT(k) + β₆TSAT²(k) + β₇TSAT³(k) + β₈ΔIron(k) + β₉Cv₁(k) + … + β_9+m-1Cv_m(k) + β₀
Ferritin model	ΔHb(k + 1) = β₁ΔESA(k) + β₂ΔESA(k)Ferr(k) + β₃ΔESA(k)Ferr²(k) + β₄ΔESA(k)Ferr³(k) + β₅Ferr(k) + β₆Ferr²(k) + β₇Ferr³(k) + β₈ΔIron(k) + β₉Cv₁(k) + … + β_9+m-1Cv_m(k) + β₀
TSAT + ferritin model	ΔHb(k + 1) = β₁ΔESA(k) + β₂ΔESA(k)TSAT(k) + β₃ΔESA(k)TSAT²(k) + β₄ΔESA(k)TSAT³(k) + β₅ΔESA(k)Ferr(k) + β₆ΔESA(k)Ferr²(k) + β₇ΔESA(k)Ferr³(k) + β₈TSAT(k) + β₉TSAT²(k) + β₁₀TSAT³(k) + β₁₁Ferr(k) + β₁₂Ferr²(k) + β₁₃Ferr³(k) + β₁₄ΔIron(k) + β₁₅Cv₁(k) + … + β_15+m-1Cv_m(k) + β₀

β = unknown regression coefficients; ΔESA = change in weight-adjusted Epoetin alfa dosing from interval k − 1 to k; ΔHb = change in hemoglobin concentration from interval k to k + 1; ΔIron = change in weight-adjusted iron dosing from interval k − 1 to k; Cv₁ through Cv_m = additional model covariates; Ferr = serum ferritin level at interval k; TSAT = transferrin saturation level at interval k.