Table 1. The PP-delivered peptide list.

closed RGD	SESANESGSRGDASYTSDESS
closed 7-RGD-7	SANESGSRGDASYTSDE
closed 5-RGD-5	NESGSRGDASYTS
closed 3-RGD-3	SGSRGDASY
1-RGD-1	SRGDA
closed 2-RGD-2	GSRGDAS
closed 2-RGD-3	GSRGDASY
closed 3-RGD-2	SGSRGDAS
closed RGE	SESANESGSRGEASYTSDESS
C-opened RGD	SDESDTNSESANESGSRGDA
C-opened RGE	SDESDTNSESANESGSRGEA
N-opened RGD	SRGDASYTSDESSDDDNDSDSH
N-opened RGE	SRGEASYTSDESSDDDNDSDSH
SSD repeats	DSSDSSDSSDSSDSSNSS
DSP	PSGNGVEEDEDTGSGDGE

Closed RGD, closed 7-RGD-7, closed 5-RGD-5, closed 3-RGD-3, and 1-RGD-1 contained 9, 7, 5, 3, and 1 juxta-amino acids at the amino- and carboxyl-terminal sides of RGD, respectively. Closed 2-RGD-2 had 2 amino acids at both sides of RGD. Closed 2-RGD-3 had two and three, and closed 3-RGD-2 had three and two amino acids at the amino- and carboxyl-terminal sides of RGD. Close RGE was the RGD-inactivated mutant of closed RGD. C-opened RGD included the RGD domain with an open carboxyl-terminal side, and C-opened RGE was the RGD-inactivated mutant of C-opened RGD. N-opened RGD included the RGD domain with an open amino-terminal side and N-opened RGE was the RGD-inactivated mutant of N-opened RGD. SSD repeats had representative SSD repeats. DSP was the well-conserved glycosaminoglycan attachment site in the dentin sialoprotein (DSP), which was the amino-terminal cleaved product of DSPP.