Table 1. Transcript expression by quantitative real time PCR in non-stimulated (NS) and LPG-stimulated NK cells (S).
Gene | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
Fold change | |||||||||
TLR2 | 0.96 | 1.06 | 1.06 | 0.53 | 0.09 | 0.18 | 0.57 | 0.10 | 0.18 |
IFN-γ | 1.04 | 1.57 | 1.13 | 2.80 | 1.00 | 0.36* | 4.08* | 1.09 | 0.26* |
TNF-α | 1.00 | 1.34 | 2.00 | 1.05 | 0.62 | 0.57 | 1.34 | 1.20 | 0.89 |
TLR2, IFN-γ and TNF-α gene expression in NK cells of healthy controls (n = 5), LCL (n = 6) and DCL (n = 3) patients.
1. C_S vs C_NS; 2. LCL_S vs LCL_NS; 3. DCL_S vs DCL_NS; 4. LCL_NS vs C_NS; 5. DCL_NS vs C_NS; 6. DCL_NS vs LCL_NS; 7. LCL_S vs C_S; 8. DCL_S vs C_S; 9. DCL_S vs LCL_S. C: healthy controls, LCL: patients with localized cutaneous leishmaniasis, DCL: patients with diffuse cutaneous leishmaniasis. *p<0.05 significant differences.