Table 1. Characteristics of all patients, and patients with and without abnormal cardiac 18F-FDOPA uptake.
| All patients | No cardiac metastases | Cardiac metastases | p-value | ||||
| Parameter | N (%) | Mean ± SD, or median (range) | N (%) | Mean ± SD, or median (range) | N (%) | Mean ± SD, or median (range) | |
| Age (y) | 116 (100) | 64±9.3 | 101 (87) | 64±8.5 | 15 (13) | 67±8.1 | NS |
| Male patients | 62 (53) | 55 (54) | 7 (47) | NS | |||
| History of | |||||||
| - Hypertension | 48 (41) | 39 (39) | 9 (60) | NS | |||
| - Atrial fibrillation | 3 (3) | 2 (1) | 0 | NS | |||
| - Myocardial infarction | 7 (6) | 6 (6) | 1 (7) | NS | |||
| Cardiac medication | |||||||
| - β blocker | 34 (29) | 28 (28) | 6 (40) | NS | |||
| - Angiotensin converting enzyme inhibitor | 18 (16) | 16 (16) | 2 (13) | NS | |||
| - Diuretic | 21 (18) | 15 (15) | 6 (40) | 0.021 | |||
| - Angiotensin II antagonist | 9 (8) | 8 (8) | 1 (7) | NS | |||
| - Statin | 28 (24) | 25 (25) | 3 (20) | NS | |||
| - Calcium channel blocker | 12 (10) | 9 (9) | 3 (20) | NS | |||
| Laboratory tests | 116 (100) | 101 (87) | 15 (13) | ||||
| Serum | |||||||
| - Creatinine (µmol/L) | 114 (98) | 84±29 | 99 (98) | 84±30 | 15 (100) | 80±6 | NS |
| - Estimated glomerular filtration rate (mL/min/1.73 m2) | 114 (98) | 77±20 | 99 (98) | 78±21 | 15 (100) | 72±18 | NS |
| - Chromogranin A (µg/L) | 116 (100) | 185 (29.0–44.6×103) | 101 (100) | 168 (29.0–44.6×103) | 15 (100) | 320 (48.0–19.1×103) | NS |
| - Platelet serotonin (nmol/109) | 116 (100) | 18 (3.8–58) | 101 (100) | 17 (3.8–48) | 15 (100) | 20 (8.2–58) | NS |
| Urine | |||||||
| - Serotonin (µmol/mol creatinine) | 98 (84) | 69 (16–1.2×103) | 89 (88) | 67 (16–1.2×103) | 9 (60) | 96 (36–4.3×102) | NS |
| - 5-Hydroxyindole acetic acid (mmol/mol creatinine) | 110 (95) | 8.5 (1.8–3.9×102) | 96 (95) | 7.3 (1.8–2.3×102) | 14 (93) | 11 (3.2–3.9×102) | NS |
| Electrocardiography | 60 (52) | 51 (50) | 9 (60) | ||||
| - Heart rate (bpm) | 60 (100) | 68±17 | 51 (100) | 68±17 | 9 (100) | 67±24 | NS |
| - Sinus rhythm | 58 (97) | 50 (98) | 8 (89) | NS | |||
| - Atrial fibrillation (n) | 2 (3) | 1 (1) | 1 (11) | NS | |||
| - PQ duration (ms) | 58 (97) | 158±23 | 50 (98) | 157±22.6 | 8 (89) | 162±23.2 | NS |
| - QRS duration (ms) | 60 (100) | 90±15 | 51 (100) | 90±15 | 9 (100) | 93±10 | NS |
| - QTc duration (ms) | 60 (100) | 416±28 | 51 (100) | 416±29.0 | 9 (100) | 420±25.0 | NS |