Table 1. Fatty acid composition of total lipids in wild-type (WT) and E2F2-/- mice liver before (0-h) and 48 hours (48-h) post-partial hepatectomy.
| Fatty acid | WT mice liver | E2F2-/- mice liver | |||||||||||||||
| 0-h | 48-h | 0-h | 48-h | ||||||||||||||
| % | % | % | % | ||||||||||||||
| 14:0 | 0.3 | ± | 0.1 | 0.8 | ± | 0.1 | 0.2 | ± | 0.04 | 0.7 | ± | 0.1 | |||||
| 14:1 n-9 | 0.04 | ± | 0.02 | 0.1 | ± | 0.04 | * | 0.04 | ± | 0.01 | 0.1 | ± | 0.03 | ||||
| 15:0 | 0.1 | ± | 0.01 | 0.1 | ± | 0.02 | 0.1 | ± | 0.01 | 0.1 | ± | 0.02 | |||||
| 15:1 n-9 | 0.01 | ± | 0.011 | 0.1 | ± | 0.01 | * | 0.03 | ± | 0.005 | 0.1 | ± | 0.01 | ||||
| 16:0 | 20.9 | ± | 0.8 | 19.7 | ± | 0.5 | * | 20.8 | ± | 1.3 | 17.9 | ± | 0.6 | ||||
| 16:1 n-9 | 2.1 | ± | 0.4 | 5.2 | ± | 1.5 | * | 2.2 | ± | 0.3 | 4.5 | ± | 0.6 | ||||
| 17:0 | 0.3 | ± | 0.05 | 0.2 | ± | 0.02 | * | 0.3 | ± | 0.02 | 0.1 | ± | 0.01 | ||||
| 17:1 n-9 | 0.2 | ± | 0.01 | 0.3 | ± | 0.03 | 0.2 | ± | 0.01 | 0.2 | ± | 0.1 | |||||
| 18:0 | 10.9 | ± | 1.3 | 3.6 | ± | 1.0 | * | 10.6 | ± | 1.4 | 3.8 | ± | 0.6 | ||||
| 18:1 n-9 | 16.7 | ± | 1.2 | 27.3 | ± | 0.8 | * | 19.5 | ± | 0.5 | 26.5 | ± | 0.7 | ||||
| 18:2 n-6 | 23.8 | ± | 1.9 | 30.8 | ± | 0.5 | * | 23.0 | ± | 2.2 | 33.5 | ± | 0.2 | # | |||
| 18:3 n-6 | 0.4 | ± | 0.1 | 0.7 | ± | 0.2 | 0.4 | ± | 0.1 | 0.6 | ± | 0.2 | |||||
| 18:3 n-3 | 0.8 | ± | 0.2 | 1.4 | ± | 0.3 | 0.8 | ± | 0.2 | 1.7 | ± | 0.2 | |||||
| 20:2 n-6 | 0.3 | ± | 0.03 | 0.6 | ± | 0.1 | 0.4 | ± | 0.1 | 0.5 | ± | 0.1 | |||||
| 20:3 n-9 | 0.5 | ± | 0.05 | 0.7 | ± | 0.02 | 0.5 | ± | 0.1 | 0.7 | ± | 0.1 | |||||
| 20:3 n-6 | 1.0 | ± | 0.1 | 0.9 | ± | 0.2 | 1.0 | ± | 0.2 | 0.8 | ± | 0.1 | |||||
| 20:4 n-6 | 11.8 | ± | 1.1 | 3.4 | ± | 0.7 | * | 11.1 | ± | 1.3 | 3.9 | ± | 0.7 | ||||
| 20:5 n-3 | 0.6 | ± | 0.2 | 0.3 | ± | 0.02 | 0.8 | ± | 0.1 | 0.4 | ± | 0.1 | |||||
| 22:4 n-6 | 0.2 | ± | 0.1 | 0.03 | ± | 0.01 | 0.2 | ± | 0.1 | 0.03 | ± | 0.02 | |||||
| 22:5 n-6 | 0.9 | ± | 0.1 | 0.5 | ± | 0.1 | 0.8 | ± | 0.1 | 0.5 | ± | 0.1 | |||||
| 22:5 n-3 | 0.9 | ± | 0.2 | 0.5 | ± | 0.1 | 0.8 | ± | 0.1 | 0.3 | ± | 0.1 | |||||
| 22:6 n-3 | 7.2 | ± | 0.8 | 3.0 | ± | 0.8 | * | 6.3 | ± | 0.4 | 3.0 | ± | 0.6 | ||||
| SFA | 32.5 | ± | 2.7 | 24.4 | ± | 1.3 | * | 32.0 | ± | 2.2 | 22.6 | ± | 1.6 | ||||
| MUFA | 19.1 | ± | 0.7 | 32.9 | ± | 1.4 | * | 21.9 | ± | 1.7 | 31.4 | ± | 2.4 | ||||
| PUFA n-6 | 38.1 | ± | 4.0 | 36.4 | ± | 1.3 | 36.5 | ± | 3.4 | 39.3 | ± | 1.8 | |||||
| PUFA n-3 | 9.5 | ± | 0.7 | 5.1 | ± | 0.4 | * | 8.7 | ± | 1.3 | 5.5 | ± | 0.4 | ||||
| n-6/n-3 | 4.0 | ± | 0.2 | 7.1 | ± | 0.9 | 4.2 | ± | 0.4 | 7.1 | ± | 0.7 | |||||
| Unsat. Index | 181.6 | 145.0 | 171.8 | 166.7 | |||||||||||||
| C16 | 23.0 | 24.9 | 23.0 | 22.4 | |||||||||||||
| C18 | 52.6 | 63.8 | 54.3 | 66.1 | |||||||||||||
| C20 | 14.2 | 5.9 | 13.8 | 6.3 | |||||||||||||
| C22 | 9.2 | 4.0 | 8.1 | 3.8 | |||||||||||||
The results are expressed as a percentage of the fatty acids measured in the corresponding total lipid sample and are the average ± SD of two independent experiments using cohorts of 6 E2F2+/+ (wild-type, WT) and 6 E2F2-/- mice each. SFA, saturated fatty acids; MUFA, monounsaturated fatty acids; PUFA, polyunsaturated fatty acids. Student's t-test for paired data: * P≤0.05 for comparisons of 48-h vs 0-h within the same genotype; # P≤.05 for comparisons of the same condition between E2F2-/- and WT groups.