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. 2014 Nov 14;9(11):e112391. doi: 10.1371/journal.pone.0112391

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© 2014 Yoshida et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Averaged crosslink density (normalized by collagen) measured with UPLC-ESI-MS/MS for all samples for A) total immature crosslink density (HLNL+DHLNL) B) total mature crosslink density (DPD+PYD), C) maturity ratio (total immature crosslink density: total mature crosslink density), and D) collagen content (per dry weight). * and ** represents statically significant difference compared to NP and d6 respectively. (One-way ANOVA ). NP = nonpregnant, d6, d12, d15, d18 = gestation day 6, 12, 15, 18, PP = postpartum. Numbers on top or below boxes are median values for each group.

Inline graphic — Averaged crosslink density (normalized by collagen) measured with UPLC-ESI-MS/MS for all samples for A) total immature crosslink density (HLNL+DHLNL) B) total mature crosslink density (DPD+PYD), C) maturity ratio (total immature crosslink density: total mature crosslink density), and D) collagen content (per dry weight). * and ** represents statically significant difference compared to NP and d6 respectively. (One-way ANOVA ). NP = nonpregnant, d6, d12, d15, d18 = gestation day 6, 12, 15, 18, PP = postpartum. Numbers on top or below boxes are median values for each group.