Table 1. Prevalence of risk alleles in intervention group (n = 92) and associated risk.
Dietary Component | Gene | Risk Allele Non-Risk Allele | Associated Risk | |
n (%) | ||||
Caffeine | CYP1A2 | 48 (52) | 44 (48) | Increased risk of myocardial infarction and hypertension when consuming above 200 mg of caffeine/day |
General recommendation: ≤300 mg/day for women of child-bearing age | ||||
≤400 mg/day for other adults | ||||
Targeted Recommendation: ≤200 mg/day for those with risk version of CYP1A2 | ||||
Vitamin C | GSTM1 + GSTT1 | 52 (57) | 40 (43) | Increased risk of serum ascorbic acid deficiency when consuming below the RDA for vitamin C |
General recommendation: RDAa for women: ≥75 mg/day | ||||
RDA for men: ≥90 mg/day | ||||
Targeted Recommendation: Same as general recommendation | ||||
Added Sugars | TAS1R2 | 41 (45) | 51 (55) | Increased risk of over-consuming sugars |
General recommendation: ≤10% energy/day | ||||
Targeted Recommendation: Same as general recommendation | ||||
Sodium | ACE | 64 (70) | 28 (30) | Increased risk of sodium-sensitive hypertension when consuming above the AI for sodium |
General recommendation: ULb: ≤2300 mg/day | ||||
Targeted Recommendation: AIc: ≤1500 mg/day for those with risk version of ACE |
RDA: Recommended dietary allowance.
UL: Tolerable upper intake level.
AI: Adequate intake.