Skip to main content
. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Appl Immunohistochem Mol Morphol. 2014 Nov-Dec;22(10):748–755. doi: 10.1097/PAI.0000000000000046

Figure 3. Lack of FLM staining of an MEN-1 glucagonoma with germline mutation K119del known tumor LOH.

Figure 3

Panel A - Centrally located tumor surrounded by a thick fibrous capsule and a smaller tumor at the low right corner (arrow) are strongly positive for glucagon (original magnification ×40). Panel B - Consecutive histological section stained with FLM demonstrates lack of immunoreactivity in both tumors. Note - tears in the section resulted from rupture of the thick fibrous tumor capsule during the antigen retrieval procedure (FLM at 1:300, original magnification ×40).