Table 4.
Bivariate Associations Between Patient Characteristics and Abnormal Geriatric Assessment or the Presence of the Frailty Syndrome
| Characteristic | Category | N (%) with Abnormal GA |
P | N (%) with Frailty |
P |
|---|---|---|---|---|---|
| Age | 60–64 | 16 (64.0) | 0.93 | 4 (16.0) | 0.61 |
| 65–69 | 9 (64.3) | 4 (28.6) | |||
| 70+ | 8 (72.7) | 3 (27.3) | |||
| Sex | Male | 21 (60.0) | 0.21 | 7 (20.0) | 0.71 |
| Female | 12 (80.0) | 4 (26.7) | |||
| Race | White | 27 (62.8) | 0.40 | 9 (20.9) | 0.64 |
| Non-White | 6 (85.7) | 2 (28.6) | |||
| Marital Status | Married | 26 (63.4) | 0.70 | 10 (24.4) | 0.66 |
| Not Married | 7 (77.8) | 1 (11.1) | |||
| Education | Graduate | 10 (62.5) | 0.93 | 4 (25.0) | 0.04 |
| College | 16 (69.6) | 2 (8.7) | |||
| High School | 7 (63.6) | 5 (45.5) | |||
| Employment | Employed | 26 (63.4) | 0.70 | 8 (19.5) | 0.39 |
| Retired | 7 (77.8) | 3 (33.3) | |||
| BMI | 17–25 | 7 (70.0) | 0.80 | 1 (10.0) | 0.61 |
| 25–30 | 14 (60.9) | 6 (26.1) | |||
| 30+ | 12 (70.6) | 4 (23.5) | |||
| Diagnosis | AML/MDS | 21 (63.6) | 0.14 | 7 (21.2) | 0.88 |
| CLL | 9 (90.0) | 2 (20.0) | |||
| Other | 3 (42.9) | 2 (28.6) | |||
| KPS | 100 | 8 (53.3) | 0.12 | 3 (20.0) | 0.78 |
| 90 | 19 (65.5) | 6 (20.7) | |||
| 80 | 6 (100.0) | 2 (33.3) | |||
| Remission at time of HCT | Yes | 13 (56.5) | 0.19 | 3 (13.0) | 0.19 |
| No | 20 (74.1) | 8 (29.6) | |||
| Ferritin Level | <400 ng/mL | 10 (71.4) | 0.74 | 2 (14.3) | 1.0 |
| ≥400 ng/mL | 21 (61.8) | 7 (20.6) | |||
| Vitamin D Level | >30 ng/mL | 7 (77.8) | 0.70 | 1 (11.1) | 0.67 |
| ≤30 ng/mL | 24 (63.2) | 8 (21.1) | |||
| BNP | <100 pg/mL | 20 (62.5) | 0.53 | 6 (18.8) | 1.0 |
| ≥100 pg/mL | 11 (73.3) | 3 (20.0) | |||
| CRP | <0.8 mg/dL | 2 (66.7) | 1.0 | 0 (0) | 1.0 |
| ≥0.8 mg/dL | 27 (64.3) | 8 (19.1) |
Abbreviations: KPS, Karnofsky Performance Status; BMI, body mass index; AML, acute myelogenous leukemia; MDS, myelodysplastic syndrome; HCT, hematopoietic cell transplantation; BNP, B-type natriuretic peptide; CRP, C-reactive protein