Table 1. Baseline clinical characteristics of the COREA cohort.
Total number of patients (n = 736) | |
Age (years; mean ± SD) | 49.9±15.4 |
Sex | |
Male | 45% |
Female | 55% |
BMI (kg/m2; mean ± SD) | 24.2±3.3 |
Atopy | |
Presence | 52% |
Absence | 48% |
Rhinosinusitis | |
Presence | 67% |
Absence | 33% |
Family history of allergic diseases | |
Presence | 47% |
Absence | 53% |
Duration of asthma (years; mean ± SD) | 9.8±11.3 |
History of exacerbation | |
Presence | 39% |
Absence | 61% |
Smoking | |
Current | 15% |
Ex- | 45% |
Non- | 40% |
Pack-years of smoking in smokers (mean ± SD) | 22.4±20.3 |
Blood eosinophils (% of total WBC; mean ± SD) | 7.3±57.5 |
Sputum eosinophils (% of total WBC; mean ± SD | 12.5±17.0 |
Log IgE (mean ± SD) | 2.3±0.7 |
Initial FEV1/FVC (%; mean ± SD) | 74.0±12.3 |
Initial FEV1 (predicted %; mean ± SD) | 81.5±21.8 |
BDR (L; mean ± SD of 457 patients) | 0.2±0.6 |
Initial severity of asthma | |
Mild intermittent | 5% |
Mild persistent | 19% |
Moderate persistent | 47% |
Severe persistent | 29% |
Abbreviations: WBC, white blood cell; BMI, Body mass index.