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. 2014 Nov 14;9(11):e112844. doi: 10.1371/journal.pone.0112844

Table 5. Multivariate analysis of risk factors for asthma-related healthcare use: Presence of hospitalizations.

Variable Unadjusted Adjusted1
OR 95% CI p OR 95% CI p
Age (per year) 1.03 1.02 1.05 <0.001 1.03 1.01 1.06 0.021
Sex (female) 1.34 0.83 2.17 0.233 1.84 0.89 3.83 0.101
Duration of asthma (per year) 1.02 1.00 1.04 0.020
BMI (per kg/m2) 1.02 0.95 1.09 0.683
History of exacerbation (presence) 2.40 1.48 3.88 <0.001 2.01 0.99 4.10 0.055
Rhinosinusitis (presence) 0.67 0.40 1.12 0.124 0.64 0.31 1.31 0.222
Family history of allergy disease (presence) 1.01 0.63 1.62 0.978
Smoking (≥10 pack-years) 1.09 0.63 1.88 0.77
FEV1 (per predicted %) 0.98 0.97 0.99 0.0003 0.99 0.97 1.01 0.174
BDR (presence) 1.20 0.60 2.39 0.604
Blood eosinophilia (per % of total WBC) 0.98 0.92 1.04 0.461
Atopy (presence) 0.93 0.47 1.83 0.825
Follow-up (maintained in the cohort) 1.05 0.64 1.73 0.843
Log IgE 0.84 0.50 1.38 0.483
ACT score variability 1.32 1.15 1.52 <0.001 1.31 1.11 1.55 0.002
Inhaler compliance score 1.02 1.00 1.03 0.062 1.00 0.99 1.02 0.723
1

Adjusted for age, sex, and variables that had a p-value <0.1 in the unadjusted model.

Abbreviations: WBC, white blood cell; BMI, Body mass index.