Table 3. Effects of combined proanthocyanidins extracted from lotus seedpod (LSPC) and Lactobacillus casei-01 (LC) on serum malondialdehyde (MDA) and total antioxidant capacity (TAOC) levels, total superoxide dismutase (T-SOD) and glutathione peroxidase (GSH-Px) activities, ratio of T-SOD to MDA (T-SOD/MDA) and ratio of GSH-Px to T-SOD (GSH-Px/T-SOD) in scopolamine-induced amnesia mice.
| Group | MDA (nmol/mL) | T-SOD (U/mL) | GSH-Px (U/mL) | TAOC (U/mL) | T-SOD/MDA | GSH-Px/T-SOD |
| CON | 24.43±9.10bc | 196.05±15.62bcd | 581.28±29.53b | 5.29±0.51bc | 8.97±2.90bcd | 2.98±0.25 |
| SCOP | 33.87±9.12a | 170.85±20.13a | 529.51±33.92a | 4.65±0.35a | 5.40±1.64a | 3.14±0.45 |
| Piracetam | 23.45±7.73bc | 201.59±18.35bcd | 604.52±17.45b | 5.19±0.28bc | 9.38±2.70cd | 3.02±0.25 |
| LC | 29.22±6.63ab | 188.01±12.95b | 602.07±24.45b | 5.03±0.20ab | 6.86±2.13ab | 3.22±0.31 |
| L-LSPC | 25.32±6.91bc | 189.67±19.60bc | 585.59±31.48b | 5.18±0.21bc | 7.80±1.44bc | 3.13±0.46 |
| H-LSPC | 23.03±5.60bc | 195.42±11.30bcd | 599.62±29.08b | 5.41±0.23c | 8.91±2.02bcd | 3.08±0.25 |
| L-LSPC+LC | 19.11±5.89c | 206.80±22.87cd | 599.66±19.67b | 6.24±0.75cd | 12.06±4.75d | 2.93±0.32 |
| H-LSPC+LC | 11.54±3.28d | 210.88±10.84d | 627.46±22.79c | 6.40±0.68d | 19.38±4.49e | 2.98±0.17 |
Notes: Means in the same column with different superscript are significantly different (P<0.05), while sharing any same letters signify insignificant differences. CON, SCOP, Piracetam and LC is control, vehicle scopolamine control, positive drug control and Lactobacillus casei-01 group, respectively. L-LSPC and H-LSPC is low and high dose of LSPC group, respectively. L-LSPC+LC is L-LSPC and LC combination group. H-LSPC+LC is H-LSPC and LC combination group.