Table 5. Effects of combined proanthocyanidins extracted from lotus seedpod (LSPC) and Lactobacillus casei-01 (LC) on brain total nitric oxide synthase (TNOS), nitric oxide synthase (iNOS) and neural nitric oxide synthase (nNOS) activities in scopolamine-induced amnesia mice.
Group | TNOS (U/mgprot) | iNOS (U/mgprot) | nNOS (U/mgprot) |
CON | 0.48±0.06b | 0.14±0.02ab | 0.34±0.08b |
SCOP | 0.60±0.05a | 0.15±0.02a | 0.45±0.05a |
Piracetam | 0.48±0.04b | 0.15±0.02a | 0.35±0.07b |
LC | 0.60±0.08a | 0.14±0.02ab | 0.46±0.07a |
L-LSPC | 0.48±0.06b | 0.15±0.01a | 0.34±0.07b |
H-LSPC | 0.45±0.09b | 0.14±0.04ab | 0.30±0.09b |
L-LSPC+LC | 0.50±0.04b | 0.16±0.02a | 0.35±0.04b |
H-LSPC+LC | 0.47±0.06b | 0.12±0.03b | 0.36±0.06b |
Notes: Means in the same column with different superscript are significantly different (P<0.05), while sharing any same letters signify insignificant differences. CON, SCOP, Piracetam and LC is control, vehicle scopolamine control, positive drug control and Lactobacillus casei-01 group, respectively. L-LSPC and H-LSPC is low and high dose of LSPC group, respectively. L-LSPC+LC is L-LSPC and LC combination group. H-LSPC+LC is H-LSPC and LC combination group.