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. 2014 Nov 14;9(11):e112715. doi: 10.1371/journal.pone.0112715

Table 1. Clinical characteristics of the subjects subdivided by BMI.

Variables Total BMI <25 kg/m2 BMI ≥25 kg/m2 P
n 1538 1245 293 -
Age (years) 51.7(44.9–56.9) 51.9(45.0–56.9) 50.0(44.6–56.9) 0.32
BMI (kg/m2) 22.7±2.8 21.7±2.0 26.9±1.6 <0.01
W (cm) 78.0(72.0–84.0) 76.0(71.0–81.0) 88.5(83.8–93.5) <0.01
VFA (cm2) 62.8(44.5–87.7) 56.7(40.9–76.8) 95.9(75.0–127.7) <0.01
SFA (cm2) 161.2(121.6–202.9) 150.2(114.2–186.9) 211.7(170.0–257.6) <0.01
SBP (mmHg) 116.0(108.0–120.7) 114.7(107.3–120.7) 120.0(110.0–122.0) <0.01
DBP (mmHg) 73.3(69.3–79.3) 72.7(69.3–79.3) 76.7(70.0–79.7) <0.01
FPG (mmol/L) 5.1±0.4 5.1±0.4 5.2±0.4 <0.01
2hPG (mmol/L) 5.8±1.1 5.8±1.0 5.9±1.1 0.04
HbA1c (%) 5.5(5.3–5.7) 5.5(5.3–5.7) 5.6(5.3–5.8) <0.01
FINS (mU/L) 6.7(4.9–9.4) 6.3(4.5–8.5) 9.6(6.7–13.1) <0.01
HOMA-IR 1.5(1.1–2.2) 1.4(1.0–2.0) 2.2(1.5–3.1) <0.01
TC (mmol/L) 4.96(4.36–5.62) 4.95(4.36–5.66) 4.97(4.36–5.55) 0.44
TG (mmol/L) 1.10(0.78–1.55) 1.04(0.75–1.48) 1.35(0.99–1.84) <0.01
HDL-c (mmol/L) 1.47(1.25–1.75) 1.51(1.28–1.77) 1.33(1.13–1.54) <0.01
LDL-c (mmol/L) 3.11(2.57–3.66) 3.06(2.54–3.65) 3.27(2.73–3.72) <0.01
ApoB (g/L) 0.78(0.68–0.89) 0.78(0.67–0.89) 0.80(0.70–0.91) <0.01
Lp(a) (mg/dL) 10.60(6.30–20.35) 10.80(6.40–20.40) 9.94(5.65–18.35) 0.15
CRP (mg/L) 0.5(0.3–1.1) 0.5(0.2–0.9) 0.8(0.4–1.6) <0.01
Dyslipidemia, N (%) 379(24.6) 302(24.3) 77(26.3) 0.47
hypercholesterolemia, N (%) 158(10.3) 142(11.4) 16(5.5) <0.01
hypertriglyceridemia, N (%) 129(8.4) 93(7.5) 36(12.3) <0.01
Low HDL-c, N (%) 98(6.4) 70(5.6) 28(9.6) 0.01
High LDL-c, N (%) 177(11.5) 150(12.0) 27(9.2) 0.17
Diabetes family history, N (%) 311(20.2) 246(19.8) 65(22.2) 0.35
CVD family history, N (%) 426(27.7) 349(28.0) 77(26.3) 0.55
Dyslipidemia family history, N (%) 225(14.6) 179(14.4) 46(15.7) 0.56
Current smoker, N (%) 347(22.6) 259(20.8) 88(30.0) <0.01

ApoB: apolipoprotein B; 2hPG: 2-h post-OGTT plasma glucose; BMI: body mass index; CRP: C reactive protein; CVD: cardiovascular disease; DBP: diastolic blood pressure; FINS: fasting insulin; FPG: fasting plasma glucose; HbA1c: glycated hemoglobin; HDL-c: high-density lipoprotein cholesterol; HOMA-IR: homeostasis model assessment-insulin resistance; LDL-c: low-density lipoprotein cholesterol; Lp(a): lipoprotein a; SBP: systolic blood pressure; SFA: subcutaneous fat area; TC: total cholesterol; TG: triglyceride; VFA: visceral fat area; W: waist circumference.

Data are presented as means ± SD or median (interquartile range 25–75%) or N (%). P for BMI ≥25 kg/m2 versus BMI <25 kg/m2.