Table 2. Presence and sex-specific expression of key sex-determining pathway genes from Caenorhabditis elegans, Drosophila melanogaster and Mus musculus.
| Name of genes | Caenorhabditis elegans | Drosophila melanogaster | Mus musculus | Crassostrea gigas |
|---|---|---|---|---|
| Xol-1 | +/+ | −/− | −/− | −/− |
| Sdc | +/+ | +/− | +/− | −/− |
| Her | +/+ | +/− | −/− | −/− |
| Tra | +/+ | +/+ | +/− | −/− |
| Fem | +/+ | +/− | +/− | +/− |
| Fog | +/+ | +/− | +/+ | −/− |
| Fru | −/− | +/+ | −/− | −/− |
| Sis | −/− | +/+ | −/− | −/− |
| Run | +/− | +/+ | +/− | +/− |
| Sxl | −/− | +/+ | −/− | −/− |
| Doa | −/− | +/+ | −/− | −/− |
| Gata4 | −/− | −/− | +/+ | +/− |
| Wt1 | −/− | −/− | +/+ | −/− |
| M33 | −/− | −/− | +/+ | −/− |
| Sf1 | −/− | −/− | +/+ | −/− |
| Mis | −/− | −/− | +/+ | −/− |
| Dax1 | −/− | −/− | +/+ | −/− |
| Sry/Sox30/SoxH | −/− | −/− | +/+ | +/+ |
| Sox9/SoxE/sox100B | −/− | +/− | +/+ | +/− |
| MAB-3/dsx/Dmrt1 | +/+ | +/+ | +/+ | +/+ |
| FoxL2 | −/− | −/− | +/+ | +/+ |
| Rspo1 | −/− | −/− | +/+ | −/− |
| Wnt4 | −/− | +/− | +/+ | +/− |
| Beta-catenin | −/− | +/− | +/+ | +/− |
The first + sign indicates presence and the second + sign indicates sex-specific expression or confirmed role in sex-determining pathways.