Table 1. Frequency of PR3-ANCA by CIA, ELISA, and aANCA in PSC vs. all controls, vs. AIH and vs. PBC.
PSC | Controls | Relevance | |||||
All PSC, n (%) | PSC, n (%) | AIH-PSC, n (%) | All Controls, n (%) | AIH, n (%) | PBC, (%) | p value | |
PR3-ANCA CIA | 94/244 (38.5%) | 82/222 (36.9%) | 12/22 (54.5%) | 27/254 (10.6%) | 14/65 (21.5%) | 12/91 (13.2%) | <0.0001a |
0.014 b | |||||||
<0.0001c | |||||||
PR3-ANCA ELISA | 57/244 (23.4%) | 51/222 (23.0%) | 6/22 (27.3%) | 6/254 (2.7%) | 5/65 (7.7%) | 0/91 (0%) | <0.0001a |
0.005b | |||||||
<0.0001c | |||||||
aANCA IIF (Titer 1∶20) | 101/244 | 89/222 (40.1%) | 12/22 (54.5%) | 51/254 (20.1%) | 26/65 (40%) | 10/91 (11%) | <0.0001a |
0.955b | |||||||
(41.4%) | <0.0001c |
p value for PSC vs. all controls.
p value for PSC vs. AIH.
p value for PSC vs. PBC.