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. 2014 Nov 14;9(11):e112877. doi: 10.1371/journal.pone.0112877

Table 1. Frequency of PR3-ANCA by CIA, ELISA, and aANCA in PSC vs. all controls, vs. AIH and vs. PBC.

PSC Controls Relevance
All PSC, n (%) PSC, n (%) AIH-PSC, n (%) All Controls, n (%) AIH, n (%) PBC, (%) p value
PR3-ANCA CIA 94/244 (38.5%) 82/222 (36.9%) 12/22 (54.5%) 27/254 (10.6%) 14/65 (21.5%) 12/91 (13.2%) <0.0001a
0.014 b
<0.0001c
PR3-ANCA ELISA 57/244 (23.4%) 51/222 (23.0%) 6/22 (27.3%) 6/254 (2.7%) 5/65 (7.7%) 0/91 (0%) <0.0001a
0.005b
<0.0001c
aANCA IIF (Titer 1∶20) 101/244 89/222 (40.1%) 12/22 (54.5%) 51/254 (20.1%) 26/65 (40%) 10/91 (11%) <0.0001a
0.955b
(41.4%) <0.0001c
a

p value for PSC vs. all controls.

b

p value for PSC vs. AIH.

c

p value for PSC vs. PBC.