Table 1. Protein homologs to core clock proteins of plants, cyanobacteria and fungi.

Organism	Protein	Clock function	C. elegans homolog	E value
Arabidopsis thaliana	CCA1	central clock	None	None
	COP1	LHY/CCA1 modulator	None	None
	DET1	LHY/CCA1 modulator	None	None
	GI	central clock	None	None
	LHY	central clock	None	None
	LUX	central clock	None	None
	PRR5	central clock	None	None
	PRR7	central clock	None	None
	PRR9	central clock	None	None
	TOC1	central clock	None	None
Synechococcus elongatus	KAI-A	central clock	None	None
	KAI-B	central clock	None	None
	KAI-C	central clock	None	None
Neurospora crassa	FRH	central clock	W08D2.7 (MTR-4)	0
	FRQ	central clock	None	None
	FWD-1	FRQ modulator	K10B2.1 (LIN-23)	1.2e-80
	VVD	central clock	F16B3.1 (EGL-2)	1.3e-06
	WC-1	central clock	F16B3.1 (EGL-2)	1.1e-05
	WC-2	central clock	F38A6.3d (HIF-1d)	3.9e-10

These proteins are the best hits found by probabilistic inference search based on Hidden Markov Models built upon multiple protein alignments of the core clock proteins of plants (A. thaliana), prokaryotes (S. elongatus) and fungi (N. crassa). Common C. elegans names are enclosed between parenthesis when available.