Table 2. Radical scavenger enzyme activities and iNOS expression in the various study groups.

	Physical exercise
Parameter	No	Yes
Arterial catalase activity, units/mg of protein
Hypercholesterolemic diet	266 ± 46	323 ± 40*
Hypercholesterolemic diet plus antioxidants	281 ± 48	305 ± 51*
Hypercholesterolemic diet plus antioxidants plus l-arginine	273 ± 46	310 ± 42*
Arterial glutathione peroxidase activity, milliunits/mg of protein
Hypercholesterolemic diet	86 ± 16	105 ± 20†
Hypercholesterolemic diet plus antioxidants	80 ± 18	95 ± 19†
Hypercholesterolemic diet plus antioxidants plus l-arginine	83 ± 16	98 ± 23†
Arterial manganese-superoxide dismutase activity, units/mg of protein
Hypercholesterolemic diet	3.6 ± 0.6	4.3 ± 0.5†
Hypercholesterolemic diet plus antioxidants	3.1 ± 0.8	4.0 ± 0.7†
Hypercholesterolemic diet plus antioxidants plus l-arginine	3.3 ± 0.6	4.1 ± 0.6†
Arterial iNOS by quantitative densitometric analysis of Western blots, arbitrary units
Hypercholesterolemic diet	0.09 ± 0.03	0.20 ± 0.07§
Hypercholesterolemic diet plus antioxidants	0.08 ± 0.02	0.19 ± 0.04§
Hypercholesterolemic diet plus antioxidants plus l-arginine	0.12 ± 0.04‡	0.23 ± 0.08¶

Data are expressed as mean ± SD.

^*P < 0.05 vs. no exercise.

^†P < 0.01 vs. no exercise.

^‡P < 0.05 vs. LDL receptor^-/- no exercise.

^§P < 0.01 vs. no exercise.

^¶P < LDL receptor^-/- antioxidants plus l-arginine no exercise.