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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Curr Opin Hematol. 2014 Sep;21(5):380–387. doi: 10.1097/MOH.0000000000000066

Table 1.

The four major classes of human thrombotic disorders

Classes of thrombotic disorders Selected examples
Atherothrombosis Coronary artery thrombosis/myocardial infarction; ischemic stroke; mesenteric artery thrombosis; limb artery thrombosis
Deep-vein thrombosis and pulmonary embolism Lower extremity; upper extremity; cerebral venous; abdomen
Immune-mediated thrombocytopenia and thrombosis HIT; antiphospholipid syndrome; sepsis syndrome; thrombosis from therapeutic monoclonal antibodies; thrombotic thrombocytopenic purpura
MCCATS Malformation, Cancer, Cardiac, Artificial surface, Trauma, Sickle cell disease

HIT is one of the immune-mediated thrombocytopenia and thrombosis disorders.

HIT, heparin-induced thrombocytopenia.