Table 1.

The dissolution efficiency of diosmin, physical mixture (PM), kneaded (KN) and freeze-dried (FD) Products.

Products	DE 10 (%)	DE 30 (%)	DE 120 (%)
Diosmin	13.37 ± 3.51	16.25 ± 4.15	17.76 ± 3.43
Physical mixture(PM)	16.50 ± 2.31	23.87 ± 1.48*	31.73 ± 3.87**
Kneaded(KN)	32.68 ± 2.81**	48.75 ± 2.29***	59.97 ± 2.05***
Freeze-Dried(FD)	43.58 ± 1.24***	63.63 ± 1.47***	77.97 ± 2.000***

Values are mean ± SD.

^* p<0.05,

^** p<0.01,

^*** p<0.001 compared with pure diosmin.