Table 1.
Maternal characteristics for singletons born with and without major congenital anomalies
| All children | Children without MCAs | Children with MCAs | ||||
|---|---|---|---|---|---|---|
| n = 349 127 | n = 339 730 | n = 9397 | ||||
| n | % | n | % | n | % | |
| Maternal age at the end of pregnancy, years (Median [interquartile range]) | 30 (26–34) | 30 (26–34) | 30 (26–34) | |||
| Townsend deprivation index | ||||||
| 1 (least deprived) | 85 160 | 24.4 | 82 850 | 24.4 | 2310 | 24.6 |
| 2 | 67 968 | 19.5 | 66 193 | 19.5 | 1775 | 18.9 |
| 3 | 68 224 | 19.5 | 66 368 | 19.5 | 1856 | 19.8 |
| 4 | 63 284 | 18.1 | 61 596 | 18.1 | 1688 | 18.0 |
| 5 (most deprived) | 47 190 | 13.5 | 45 850 | 13.5 | 1340 | 14.3 |
| Missing | 17 301 | 5.0 | 16 873 | 5.0 | 428 | 4.6 |
| Ever smoked before delivery | 132 934 | 38.1 | 129 415 | 38.1 | 3519 | 37.4 |
| BMI before pregnancy (kg/m2) | ||||||
| Underweight (<18.5) | 11 335 | 3.2 | 11 026 | 3.2 | 309 | 3.3 |
| Normal (18.5–24.9) | 154 140 | 44.2 | 150 128 | 44.2 | 4012 | 42.7 |
| Overweight (25–29.9) | 58 998 | 16.9 | 57 407 | 16.9 | 1591 | 16.9 |
| Obese (30–39.9) | 32 130 | 9.2 | 31 154 | 9.2 | 976 | 10.4 |
| Missing | 92 524 | 26.5 | 90 015 | 26.5 | 2509 | 26.7 |
| Diabetes | 1619 | 0.5 | 1521 | 0.4 | 98 | 1.0 |
| Hypertension | 919 | 0.3 | 877 | 0.3 | 42 | 0.4 |
| Asthma | 26 981 | 7.7 | 26 204 | 7.7 | 777 | 8.3 |
| Epilepsy | 1431 | 0.4 | 1353 | 0.4 | 78 | 0.8 |