Figure 1.

Permissiveness of medulloblastoma cells for parvovirus H-1 (H-1PV) infection and onset of replication Medulloblastoma cells or infant non-transformed astrocytes were infected with 1 plaque forming unit per cell of wild type H-1PV, fixed after 24 h, and examined by confocal microscopy after immunofluorescence staining for the nuclear membrane protein Lamin beta (green) and for the viral protein NS-1 (red). (a) Representative pictures of indicated cell cultures after mock (three left panels) or H-1PV infection (three right panels). (b) The proportion of NS1-expressing medulloblastoma cells in a field was determined in triplicates by manual counting. Error bars indicate standard errors of the mean.