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Accumulation of autofluorescent material throughout the cerebrum of a Mcoln1−/− mouse. Large amounts of autofluorescence are evident in cell bodies of the neocortex, the CA1 region of the hippocampus, and the cerebellum of a Mcoln1−/− mouse compared to a Wt mouse. Scale bar equals 50 μm and pertains to all panels.
