Skip to main content
. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Eur J Immunol. 2014 Oct 1;44(11):3273–3282. doi: 10.1002/eji.201444800

Figure 1.

Figure 1

Lineage-restricted Dk expression specifically affects G2+ NK cells. (A) Lethally irradiated Tg-Dk (T) and non-Tg (N) mice were reconstituted with Tg-Dk (T-T or T-N) or non-Tg BM (N-T or N-N), respectively. Representative histograms show isotype control (filled) and Dk (open) staining on peripheral leukocytes for the indicated BMT recipients 10–12 wk post-transplantation. (B) Representative histograms show expression of NK cell receptors and maturation markers (CD27 and CD11b) (open) and isotype control (filled) on live, gated NK cells (CD3− CD19− NKp46+) from indicated mice. (C) Bars represent the mean (±SEM) percentage and mean fluorescence intensity (MFI) for defined NK receptors for the indicated BMT recipients. *p < 0.05; **p < 0.01; ***p < 0.001 compared with T-T. Data are representative of three independent experiments. Each experiment contains 4–5 mice per group.