Table 2.
Unadjusted STI incidence rates and incidence rate ratios comparing pre- and on-ART periods among HIV patients in South Africa.
| Characteristic | Crude incidence rates (95% CL) per 100 person-years of observation |
Incidence rate ratio (95% CL) (Pre/On-ART) | ||
|---|---|---|---|---|
| Overall | Pre-ART | On-ART | ||
|
|
||||
| Overall | 5.50 (5.43, 5.58) | 9.57 (9.44, 9.70) | 1.29 (1.24, 1.34) | 6.91 (4.68, 10.19) |
| Gender | ||||
| Male | 6.15 (6.00, 6.29) | 11.97 (11.68, 12.27) | 1.57 (1.48, 1.66) | 7.63 (4.03, 14.45) |
| Female | 5.23 (5.15, 5.32) | 8.73 (8.58, 8.88) | 1.29 (1.23, 1.36) | 6.75 (4.13, 11.03) |
| Age at study entry (years) | ||||
| <25 | 7.51 (7.33, 7.69) | 10.55 (10.28, 10.83) | 2.66 (2.48, 2.84) | 3.97 (1.97, 8.03) |
| 25 – 34 | 6.15 (6.04, 6.26) | 10.87 (10.67, 11.08) | 1.49 (1.42, 1.57) | 7.28 (4.32, 12.28) |
| ≥35 | 2.90 (2.81, 3.00) | 5.92 (5.72, 6.14) | 0.59 (0.53, 0.65) | 10.12 (3.57, 28.67) |
| CD4 count at ART start | ||||
| <200 | 4.51 (4.42, 4.59) | 8.80 (8.62, 8.97) | 1.30 (1.24, 1.36) | 6.76 (4.18, 10.92) |
| ≥200 | 7.26 (7.12, 7.40) | 10.49 (10.28, 10.70) | 1.62 (1.51, 1.73) | 6.48 (3.28, 12.81) |
| WHO stage at ART start | ||||
| Stages 1 and 2 | 6.18 (6.10, 6.27) | 10.55 (10.39, 10.71) | 1.51 (1.45, 1.57) | 6.98 (4.63, 10.50) |
| Stages 3 and 4 | 1.83 (1.73, 1.94) | 3.19 (2.98, 3.41) | 0.80 (0.71, 0.90) | 3.98 (1.08, 14.71) |
| Pregnant at ART starta | ||||
| Yes | 4.69 (4.48, 4.91) | 8.60 (8.20, 9.03) | 0.96 (0.84, 1.11) | 8.92 (2.06, 38.62) |
| No | 5.32 (5.23,5.41) | 8.75 (8.59, 8.92) | 1.35 (1.28, 1.42) | 6.48 (3.84, 10.91) |
| TB at ART start | ||||
| Yes | 3.29 (3.17, 3.40) | 4.80 (4.60, 5.00) | 1.86 (1.74, 1.98) | 2.58 (1.19, 5.61) |
| No | 6.14 (6.06, 6.23) | 10.89 (10.72, 11.05) | 1.24 (1.19, 1.30) | 8.76 (5.52, 13.90) |
CL, Confidence Limits; ART, Anti-retroviral Therapy;
a
Only among women