Table 2.
Overall (n=285) |
MW-LGE + (n=34) |
MW-LGE − (n=251) |
P | |
Cardiac Magnetic Resonance | ||||
Left Ventricular Function | ||||
Ejection fraction (%) | 27 ± 8 | 24 ± 9 | 28 ± 8 | 0.02 |
Stroke volume (ml) | 60 ± 23 | 68 ± 40 | 59 ± 19 | 0.22 |
(ml/m2) | 31 ± 11 | 34 ± 21 | 31 ± 9 | 0.42 |
Cardiac Output (L/min) | 4.7 ± 1.9 | 5.6 ± 3.2 | 4.6 ± 1.6 | 0.09 |
(L-m2/min) | 2.4 ± 0.9 | 2.8 ± 1.7 | 2.4 ± 0.7 | 0.20 |
Left Ventricular Remodeling Indices | ||||
End-diastolic volume (ml) | 230 ± 78 | 287± 93 | 223 ± 73 | <0.001 |
(ml/m2) | 119 ± 37 | 141 ± 45 | 116 ± 35 | <0.001 |
End-systolic volume (ml) | 170 ± 72 | 218 ± 90 | 163 ± 67 | 0.001 |
(ml/m2) | 88 ± 35 | 107 ± 43 | 85 ± 33 | 0.001 |
Myocardial mass (gm) | 192 ± 56 | 219 ± 56 | 188 ± 55 | 0.003 |
(gm/m2) | 99 ± 26 | 108 ± 24 | 98 ± 26 | 0.04 |
Concentricity (gm/ml) | 0.9 ± 0.2 | 0.8 ± 0.2 | 0.9 ± 0.2 | 0.12 |
Anteroseptal wall thickness (cm) | 1.0 ± 0.2 | 1.0 ± 0.2 | 1.0 ± 0.2 | 0.41 |
Posterolateral wall thickness (cm) | 0.9 ± 0.2 | 0.9 ± 0.2 | 0.9 ± 0.2 | 0.88 |
Peak Systolic Wall stress (kPa) | 34 ± 8.8 | 37 ± 10 | 33 ± 9 | 0.02 |
Left Atrial Geometry | ||||
Diameter (cm) | 4.2 ± 0.7 | 4.3 ± 0.6 | 4.2 ± 0.7 | 0.38 |
Area (cm2) | 27 ± 7 | 31 ± 7 | 26 ± 7 | <0.001 |
(cm2/m2) | 14 ± 4 | 15 ± 3 | 14 ± 4 | 0.06 |
Overall (n=206) |
MW-LGE + (n=22) |
MW-LGE − (n=184) |
P | |
Transthoracic Echocardiography* | ||||
Left Ventricular Function | ||||
Ejection fraction (%) | 26 ± 10 | 23 ± 10 | 27 ± 9 | 0.10 |
Left Ventricular Remodeling Indices | ||||
End-diastolic diameter (cm) | 6.2 ± 0.8 | 6.7 ± 1.1 | 6.2 ± 0.8 | 0.04 |
End-systolic diameter (cm) | 5.5 ± 0.9 | 6.0 ± 1.2 | 5.4 ± 0.9 | 0.04 |
Myocardial mass (gm) | 249 ± 70 | 288 ± 70 | 243 ± 68 | 0.004 |
(gm/m2) | 128 ± 33 | 142 ± 31 | 126 ± 33 | 0.03 |
Relative wall thickness (cm) | 0.30 ± 0.06 | 0.29 ± 0.09 | 0.30 ± 0.06 | 0.61 |
Left Atrial Geometry | ||||
Diameter (cm) | 4.4 ± 0.8 | 4.5 ± 1.0 | 4.3 ± 0.8 | 0.33 |
Available in 72% of the population (mean interval of 1.7 ± 3.0 days of CMR)