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. 2014 Sep 17;307(10):C920–C927. doi: 10.1152/ajpcell.00029.2014

Fig. 4.

Fig. 4.

Thrombus formation and tail bleeding time of platelets from sphk1−/− and sphk1+/+ mice. A: original phase contrast images (left) of surface coverage by adherent platelets and arithmetic means ± SE (n = 6, right) following perfusion of whole blood from sphk1+/+ (black bar) and sphk1−/− (grey bar) mice over a collagen-coated surface for 5 min at high (1,700−s) arterial shear rates. Scale bar equals 50 μm. *P < 0.05, statistically significant difference from sphk1+/+ platelets. B: arithmetic means ± SE (n = 14) of tail bleeding time measured after amputating the tail tip of sphk1+/+ (black dots) and sphk1−/− (grey dots) mice. Each dot represents 1 individual; black bar represents the mean value.