Fig. 3.

Venn diagram illustrating number of genes significantly upregulated (red) and downregulated (green) by obesity in each of the 15 arteries organized by muscle. This figure illustrates the overlapping vascular effects of obesity within each muscle. Overlap of the circles of 2 arteries indicates arteries that had the same altered gene expression. Thus, the center overlap contains a subset of genes whose expression was changed in all arteries of that muscle/artery. For example, in the gastrocnemius with white portion there were 25 genes whose expression was upregulated and 11 genes whose expression was downregulated in all arteries/arterioles sampled from this muscle. The total number of genes interrogated was 10,447.