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Relaxation responses to isoproterenol in TG6 and TG8 mice. A: extent of relaxation in TG6 mice, which had an intermediate level of Gαs ASM protein expression, compared with TG1 and TG8 mice, was greater than in NTG littermates. B: TG8 mouse airways, which had no detectable increase in ASM Gαs protein expression, showed no differences in the relaxation response to isoproterenol compared with NTG. Values are means ± SE; n = 4 mice in each group. *P < 0.05 vs. NTG.
