Table 1.
|
|
|
Peak |
Flanking markers
c
|
|
|
|
Estimate
d
|
|
|
|
|
---|---|---|---|---|---|---|---|---|---|---|---|---|
Chr | Trait a | Groups | (cM) b | Left | Right | F-value | LOD | a | s.e a | d | s.e d | % var e |
1 |
Gastro** |
pQTL |
23 |
rs3696088 |
rs13472794 |
35.40 |
14.84 |
-0.0417 |
0.0054 |
-0.0239 |
0.0073 |
6.73 |
1 |
Pec** |
pQTL |
23 |
rs3696088 |
rs13472794 |
53.84 |
22.19 |
-0.0084 |
0.0089 |
-0.0503 |
0.0120 |
9.88 |
1 |
Tnni1 |
eQTL |
23 |
rs3696088 |
rs13472794 |
8.73 |
3.75 |
-0.3433 |
0.0965 |
-0.2555 |
0.1282 |
2.23 |
1 |
AI** |
pQTL |
24 |
rs3696088 |
rs13472794 |
13.00 |
5.57 |
0.0813 |
0.0165 |
0.0332 |
0.0219 |
2.64 |
1 |
Fat** |
pQTL |
24 |
rs3696088 |
rs13472794 |
13.54 |
5.80 |
0.0817 |
0.0167 |
0.0367 |
0.0222 |
2.68 |
1 |
Edl** |
pQTL |
25 |
rs3696088 |
rs13472794 |
7.19 |
3.10 |
-0.0327 |
0.0086 |
0.0010 |
0.0112 |
1.44 |
2 |
Edl |
pQTL |
78 |
rs3144393 |
rs13476878 |
6.79 |
2.93 |
-0.0179 |
0.0052 |
0.0107 |
0.0082 |
1.36 |
2 |
Gastro** |
pQTL |
80 |
rs3144393 |
rs13476878 |
9.40 |
4.04 |
-0.0117 |
0.0033 |
0.0124 |
0.0053 |
1.88 |
2 |
AI** |
pQTL |
88 |
rs3144393 |
rs13476878 |
18.65 |
7.95 |
0.0519 |
0.0091 |
-0.0263 |
0.0138 |
3.65 |
2 |
Fat** |
pQTL |
88 |
rs3144393 |
rs13476878 |
19.62 |
8.35 |
0.0535 |
0.0092 |
-0.0279 |
0.0140 |
3.84 |
3 |
Pec |
pQTL |
44 |
rs13477174 |
rs3670634 |
9.84 |
4.23 |
0.0143 |
0.0049 |
0.0243 |
0.0069 |
1.96 |
3 |
Gastro |
pQTL |
56 |
rs3663873 |
rs13477430 |
6.51 |
2.81 |
0.0084 |
0.0032 |
0.0134 |
0.0050 |
1.31 |
3 |
Edl |
pQTL |
64 |
rs3663873 |
rs13477430 |
5.45 |
2.35 |
0.0179 |
0.0058 |
0.0145 |
0.0103 |
1.10 |
4 |
IGF1 |
eQTL |
68 |
rs6324470 |
rs3659226 |
8.46 |
3.63 |
0.0985 |
0.0312 |
-0.1273 |
0.0516 |
2.17 |
5 |
Gastro |
pQTL |
49 |
rs6256504 |
CEL-5_52953963 |
4.51 |
1.95 |
-0.0050 |
0.0030 |
0.0113 |
0.0048 |
0.91 |
6 |
Gastro |
pQTL |
0 |
- |
rs13478602 |
6.64 |
2.86 |
-0.0058 |
0.0028 |
0.0125 |
0.0041 |
1.33 |
6 |
AI** |
pQTL |
27 |
rs13478727 |
rs13478839 |
10.27 |
4.41 |
0.0393 |
0.0090 |
-0.0121 |
0.0136 |
1.99 |
6 |
Fat** |
pQTL |
28 |
rs13478727 |
rs13478839 |
9.97 |
4.29 |
0.0394 |
0.0091 |
-0.0122 |
0.0137 |
1.98 |
6 |
lengthNT** |
pQTL |
45 |
rs3676254 |
rs3656205 |
13.45 |
5.76 |
0.2921 |
0.0578 |
0.1200 |
0.0975 |
2.58 |
7 |
Gastro |
pQTL |
47 |
rs3676254 |
rs3656205 |
5.65 |
2.44 |
0.0227 |
0.0068 |
-0.017 |
0.0073 |
1.14 |
7 |
Pec** |
pQTL |
47 |
rs3676254 |
rs3656205 |
10.54 |
4.53 |
0.0445 |
0.0113 |
-0.0169 |
0.0122 |
2.10 |
8 |
Gastro |
pQTL |
37 |
rs13479657 |
rs13479757 |
7.22 |
3.11 |
0.0134 |
0.0036 |
-0.0032 |
0.0060 |
1.45 |
8 |
Fat** |
pQTL |
68 |
rs3678433 |
rs6182338 |
15.00 |
6.42 |
0.0556 |
0.0102 |
0.0022 |
0.0163 |
2.96 |
8 |
AI** |
pQTL |
69 |
rs3678433 |
rs6182338 |
15.38 |
6.58 |
0.0546 |
0.0100 |
0.0032 |
0.016 |
2.95 |
9 |
Gastro |
pQTL |
0 |
- |
rs13480071 |
4.28 |
1.85 |
-0.0039 |
0.0029 |
-0.0100 |
0.0039 |
0.86 |
9 |
AI |
pQTL |
23 |
rs8259427 |
rs6213724 |
8.94 |
3.85 |
0.0311 |
0.0091 |
0.0334 |
0.0139 |
1.79 |
9 |
Fat |
pQTL |
23 |
rs8259427 |
rs6213724 |
9.18 |
3.95 |
0.0320 |
0.0091 |
0.0336 |
0.0140 |
1.83 |
10 |
lengthNT |
pQTL |
26 |
rs13480578 |
CEL-10_58149652 |
7.96 |
3.43 |
0.1970 |
0.0519 |
-0.0946 |
0.0792 |
1.58 |
10 |
Gastro |
pQTL |
30 |
rs13480579 |
CEL-10_58149653 |
4.50 |
1.94 |
-0.0082 |
0.0028 |
-0.0033 |
0.0041 |
0.91 |
11 |
Tail** |
pQTL |
25 |
rs6276300 |
rs6199956 |
16.87 |
7.21 |
0.2461 |
0.0425 |
0.024 |
0.0682 |
3.29 |
11 |
lengthNT** |
pQTL |
26 |
rs6276300 |
rs6199956 |
21.55 |
9.16 |
0.3596 |
0.0556 |
0.0833 |
0.0892 |
4.15 |
11 |
BMI |
pQTL |
49 |
rs13481054 |
rs3701609 |
8.23 |
3.55 |
0.5312 |
0.1385 |
0.2684 |
0.1978 |
1.64 |
11 |
Gastro |
pQTL |
68 |
rs3653651 |
rs13481216 |
4.86 |
2.10 |
0.0086 |
0.0028 |
0.0026 |
0.0040 |
0.98 |
14 |
Gastro |
pQTL |
34 |
rs8251329 |
rs3712401 |
7.77 |
3.35 |
0.0118 |
0.0030 |
0.0030 |
0.0042 |
1.56 |
17 |
AI** |
pQTL |
17 |
rs13482893 |
rs3719497 |
11.2 |
4.81 |
0.0418 |
0.0091 |
-0.0079 |
0.0145 |
2.14 |
17 |
Fat** |
pQTL |
17 |
rs13482893 |
rs3719497 |
10.94 |
4.70 |
0.0415 |
0.0091 |
-0.0097 |
0.0144 |
2.14 |
17 |
Edl** |
pQTL |
33 |
rs3023442 |
rs6395919 |
7.74 |
3.34 |
-0.0187 |
0.0049 |
0.0072 |
0.0079 |
1.55 |
17 |
Gastro** |
pQTL |
68 |
rs6257479 |
rs3663966 |
9.62 |
4.14 |
-0.0128 |
0.0029 |
0.0024 |
0.0042 |
1.92 |
18 |
lengthNT |
pQTL |
34 |
rs3670254 |
rs3718618 |
8.39 |
3.62 |
0.2128 |
0.0522 |
0.0373 |
0.078 |
1.67 |
18 | lengthNA | pQTL | 35 | rs3670254 | rs3718618 | 8.62 | 3.72 | 0.1345 | 0.0325 | 0.0149 | 0.0486 | 1.71 |
aTrait abbreviations: lengthNA nasal to anal length (cm), lengthNT nasal to tail length (cm), AI adiposity index, BMI body mass index, Tail tail length (cm), Soleus soleus muscle weight percentage, Gastro gastrocnemius muscle weight percentage, Edl EDL muscle weight percentage, Pec pectoralis muscle weight percentage, Fat average gonadal fat pad weight percentage (epididymal for males and perimetrial for females). Tnni1 troponin I type 1 expression, IGF1 insulin-like growth factor 1 expression. QTL with an F-value that exceeded 1% genome-wide permutation threshold are denoted by **; QTL without ** exceeded 5% genome-wide permutation threshold.
bPeak position of QTL detected in Kosambicentimorgans.
cFlanking markers (left and right) of the QTL peak. A“-“ notation denotes the end of the chromosome. See Additional file 1: Table S6 for marker information.
da: additive effect; s.ea: standard error of additive effect; d: dominance effect; s.ed: standard error of dominance effect.
e% var: percentage of phenotypic variance that a given QTL position could account for.