Table 3.
|
|
|
Position |
Flanking markers
c
|
am + dm + im
d
|
am + dm
e
|
am
g
|
||||
---|---|---|---|---|---|---|---|---|---|---|---|
Chr | Trait a | Groups | (cM) b | Left | Right | P -value | %var | P -value | %var | P -value | % var |
1 |
BMI |
pQTL |
22 |
rs3696088 |
rs13472794 |
7.35E-02 |
0.70 |
3.85E-02 |
0.65 |
8.48E-03 |
0.69 |
1 |
Gastro |
pQTL |
24 |
rs3696088 |
rs13472794 |
2.45E-08 |
3.58 |
1.77E-08 |
3.34 |
1.49E-01 |
0.20 |
1 |
Pec |
pQTL |
25 |
rs3696088 |
rs13472794 |
3.95E-12 |
5.06 |
1.08E-11 |
4.56 |
3.52E-03 |
0.80 |
2 |
P/D |
tQTL |
61 |
rs13476636 |
rs3144393 |
2.66E-04 |
2.64 |
1.56E-04 |
2.43 |
1.52E-04 |
2.00 |
3 |
Pec |
pQTL |
43 |
rs13477174 |
rs3670634 |
2.31E-02 |
0.95 |
1.02E-02 |
0.91 |
8.95E-02 |
0.29 |
3 |
Atp2a2 |
eQTL |
120 |
rs3724562 |
CEL-3_159340478 |
8.87E-03 |
1.57 |
7.31E-03 |
1.34 |
3.72E-03 |
1.14 |
6 |
Fat |
pQTL |
27 |
rs13478727 |
rs13478839 |
4.24E-03 |
1.31 |
1.36E-03 |
1.31 |
2.74E-04 |
1.31 |
6 |
lengthNT |
pQTL |
69 |
UT_6_123.37228 |
rs3688358 |
1.34E-01 |
0.55 |
7.28E-02 |
0.52 |
3.65E-02 |
0.43 |
8 |
AI |
pQTL |
20 |
rs13479657 |
rs13479757 |
1.42E-02 |
1.04 |
5.09E-03 |
1.04 |
1.14E-03 |
1.04 |
8 |
Fat |
pQTL |
20 |
rs13479657 |
rs13479757 |
1.15E-02 |
1.10 |
4.13E-03 |
1.09 |
9.01E-04 |
1.09 |
8 |
Igf2 |
eQTL |
33 |
rs13479657 |
rs13479757 |
6.63E-02 |
1.10 |
3.30E-02 |
1.05 |
8.20E-01 |
0.01 |
14 |
BMI |
pQTL |
63 |
rs3709178 |
rs13482404 |
9.57E-02 |
0.63 |
4.50E-02 |
0.62 |
1.23E-01 |
0.24 |
17 |
Fat |
pQTL |
15 |
rs13482893 |
rs3719497 |
4.84E-02 |
0.74 |
3.38E-02 |
0.65 |
1.44E-02 |
0.64 |
17 |
AI |
pQTL |
28 |
rs3023442 |
rs6395919 |
3.76E-02 |
0.83 |
2.68E-02 |
0.71 |
7.06E-03 |
0.71 |
17 |
Soleus |
pQTL |
69 |
rs6257479 |
rs3663966 |
3.77E-02 |
0.86 |
1.82E-02 |
0.81 |
3.49E-02 |
0.45 |
18 |
AI |
pQTL |
42 |
rs3718618 |
rs13483438 |
3.92E-02 |
0.82 |
2.97E-02 |
0.69 |
4.65E-02 |
0.39 |
18 |
Fat |
pQTL |
42 |
rs3718618 |
rs13483438 |
3.27E-02 |
0.87 |
2.78E-02 |
0.71 |
4.88E-02 |
0.39 |
X |
Atp2a2 |
eQTL |
54 |
rs13484003 |
rs13484087 |
1.74E-04 |
2.69 |
1.11E-04 |
2.46 |
1.96E-03 |
1.30 |
X | Egf | eQTL | 56 | rs13484003 | rs13484087 | 3.34E-02 | 1.18 | 1.75E-02 | 1.10 | 1.33E-02 | 0.83 |
aTrait abbreviations are the same as in Table 1. P/D: total protein/total DNA. Atp2a2: ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 expression. Igf2: insulin-like growth factor 2 expression. Egf: epidermal growth factor expression.
bPeak position of QTL detected in Kosambi centimorgans.
cFlanking markers (left and right) of the QTL peak. See Additional file 1: Table S6 for marker information.
dam + dm + im tested the overall interaction, which included additive, dominance, and imprinted pQTL by Myostatin genotype interactions. P-value < 0.05 is shown in italics %var: percentage of phenotypic variance accounted for at QTL position.
eam + dm tested for non-imprinted interactions, which included additive and dominance pQTL by Myostatin genotype interactions. P-value < 0.05 is shown in italics %var: percentage of phenotypic variance accounted for at QTL position.
fam tested for additive interactions, which included additive pQTL by Myostatin genotype interactions. P-value < 0.05 is shown in italics % var: percentage of phenotypic variance accounted for at QTL position.