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. 2014 Nov 17;4:7074. doi: 10.1038/srep07074

Figure 5.

Figure 5

(A) Force-indentation curve of representative normal SH-SY5Y cells. The fitting curve was obtained by fitting the measured curve using the Sneddon model. (B) Frequency distribution of Young's modulus of representative normal SH-SY5Y cells. The solid curve was fitted by Gaussian distribution. (C) Statistical comparison of Young's modulus of SH-SY5Y cells under different conditions: without treatment (control); with 200 μM NMDA treatment for 1 h; with 10 μM MK801 treatment for 1 h; with 200 μM NMDA and 10 μM MK801 treatment for 1 h. (D) Statistical comparison of Young's modulus of SH-SY5Y cells under different conditions: without treatment (control); with 50 μM NMDA treatment for 1 h; with 10 μM MK801 treatment for 1 h; with 50 μM NMDA and 10 μM MK801 treatment for 1 h. Statistical analysis was conducted by SPSS using One-way ANOVA followed by Newman-Keuls post hoc test (**p<0.01). Data are represented as mean ± SEM (30 samples in triplicates for each condition).