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. 2014 Oct 12;5(11):1254–1258. doi: 10.1021/ml500344j

Table 4. In Vitro Inhibition of COX-1 in OVCAR3 and COX-2 in 1483 HNSCC Cell Line Assay Data of Promising Compounds.

no. OVCAR3 COX-1 IC50 (μM)a 1483 HNSCC COX-2 IC50 (μM)a
19 2.80 >5
23 0.78 >5
27 0.18 >5
28 0.36 >5
30 >4 >5
a

IC50 values were determined as described previously13,17 for OVCAR3 or 1483 HNSCC cells.